Cytokeratin 1 anticorps (C-Term) (CF®568)

N° du produit ABIN7655836

Cet anticorps Souris Monoclonal détecte spécifiquement Cytokeratin 1 dans IHC et IHC (fp). Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Cytokeratin 1 anticorps (C-Term) (CF®568) (ABIN7655836)

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 1 est conjugé à/à la CF®568

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: LHK1

Détail du produit anti-Cytokeratin 1 anticorps (CF®568)

Épitope: C-Term

Fonction: Cytokeratin 1 (Suprabasal Keratinocyte Marker)(LHK1), CF568 conjugate

Attributs du produit: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Skin or Cervix.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Cytokeratin 1

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Autre désignation: Keratin 1

Sujet:

Synonyms: 67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1

Gene Symbol: KRT1

Tissue Expression: Epithelial cells

Poids moléculaire: 67 kDa

ID gène: 38748

UniProt: P04264